The diet-induced obesity model (DIO model) is an animal model used to study obesity using animals that have obesity caused by being fed high-fat or high-density diets. It is intended to mimic the most common cause of obesity in humans.  These animals can then be used to study in vivo obesity, obesity's comorbidities, and other related diseases.

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A wide range of different animal models is currently being used to elucidate the mechanisms underlying diabetes mellitus as well as identify novel treatments, including spontaneous, induced and transgenic models. Chemically-induced rodent models of type 1 diabetes are typically established with an injection of streptozotocin (STZ), a type of β-cell toxic agents that can induce hyperglycemia within a few days of administration. 

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Rats provide an excellent model for skin wound healing by allowing the standardization of the type, size, shape, and depth of the wound injury, which facilitates comparison of data between studies of healing in all mammalian species. Despite species differences, the availability of animals with well-defined health and genetic backgrounds along with a bounty of literature documenting biological responses and parameters for rats allows the rat to serve as a valuable research tool in the search for faster, stronger, and more anatomically correct wound healing with the ultimate goal of exact skin replacement.

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We uses a transgenic mice express human ACE2, the receptor for severe acute respiratory syndrome coronavirus (SARS-CoV) to gain cellular entry.

Acute toxicity use death of animals as an endpoint to assess the toxic level of a chemical (or products). By using a step wise testing method, in vivo testing enable us to classify the chemicals toxicity level based on LD50. It is a safety data foundation that prepare a product for clinical trial assessment. 

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Stem cell therapy is gaining much popularity, thanks to their immunomodulatory properties. With the administration of MSC intravenously, several studies have shown that a small proportion of infused MSCs can traffic to the draining lymph nodes (LNs). This is accompanied with an increase of different types of regulatory immune cells in the LNs, suggesting the importance of migration of MSCs to the LNs in order to contribute to immunomodulatory response. Hence, the traffic detection of MSC following administration can have indication on its clinical safety and efficiency.  

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Methicillin-resistant Staphylococcus aureus (MRSA) are nosocomial-related, Gram-positive bacteria that have been known to display multidrug-resistance (MDR) properties towards a wide range of structurally unrelated antibiotics and antimicrobial agents. We uses proprierary in vivo wound modela and state of art ABSL-2 animal facility to assess anti-microbial activity of products 

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Osteoporosis is a metabolic bone disease characterized by decreased bone density and degeneration of bone microarchitecture. Male osteoporosis is not as prevalent as female postmenopausal osteoporosis. With bilateral orchidectomy, a model of testosterone deficient induced osteoporosis is established. This model can be utilized to assess the potential of products in alleviating osteoporosis

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